ANALYSIS OF SMALL MOLECULE INTERACTION WITH DNA

Abstract

The work embodied in this thesis entitled "Analysis of small molecule interaction with DNA" was initiated August, 2009. The thesis consists of a preamble of the present work and two chapters. DNA interaction studies on mononuclear complexes of iron and manganese derived from planar tetradentate ligand is described in chapter 1. In chapter 2, synthesis and characterization of new mononuclear Fe(II) complex and DNA interaction studies will be described. All the ligands and complexes described in this thesis were characterized by elemental analysis followed by spectral analysis. In keeping with general practice of reporting scientific observations, due acknowledgement has been made of the findings of other investigators. I must take the responsibility of any unintentional oversights and error which might have crept in.