A NANO INSPIRED HERBAL BANDAGE FOR CRITICAL WOUND MANAGEMENT

Abstract

A wound can be understood as an irregularity or discontinuity of the skin, tissue because physical, chemical or biological insult. Wound are classified in many ways such as based on etiology, integrity of skin, wound depth, degree of contamination and duration of wound healing. Repair or rreplacement of damaged tissue by healthy tissue is known as wound healing. Various factors can meddle with at least one stage of wound healing cycle, thus causing wound not healed properly. These factor are oxygenation, pathogen, age of patient, habits of drinking and smoking, sex hormones, stress, diabetes condition and nutrition. Nanotechnology is game changing field for Biotechnology. Nanotechnology have tremendous application in biotechnology and biomedical. Herbal bandage consist of two layer named hydrogel and nanomat. Hydrogel is a suitable and promising solution for treatment of wound. Nanoparticles based scaffold are promising treatment strategies for accelerating wound healing diabetic and infected wound. Nanoparticles are smaller in size, size and shape dependent physiochemical properties. Nanomaterial have large surface area to volume ratio that increases interaction between cell and nanomaterial, high drug loading capacity and diffuse into wound site. Nanomaterials have many application in field of biology and biomedical science such as topical delivery of drugs, controlled release of drug, targeted drug delivery, better cell interactions, cell proliferation, required for effective wound healing. Nanomaterial those have antibacterial, anti-inflammatory, antioxidant, biocompatibility, biodegradability, nontoxic and better cell viability properties can be used wound healing application.