DEVELOPMENT OF PROTEIN-NANOFIBER COMPOSITE AS HERBAL BANDAGE TOWARDS CLINICAL WOUND HEALING

Abstract

This research looks at the potential benefits of PCL (polycaprolactone), Collagen, and clove oil-based nanofibers for wound healing.To investigate the characteristics of the nanofibers, several characterization techniques such as FESEM, FTIR, Modular Compact Rheometer, TGA, and Antimicrobial test were used. FESEM pictures revealed homogenous and fine fibers with a diameter of around 300 nm. The effective integration of clove oil within the nanofibers was confirmed by FTIR analysis. Mechanical investigation with a Modular Compact Rheometer revealed that the nanofibers had acceptable mechanical characteristics. TGA analysis revealed that the nanofibers were thermally stable. The antibacterial test demonstrated the nanofibers’ potential for wound healing applications. Based on these findings, PCL collagen loaded with clove oil nanofibers offer promising wound healing characteristics.