DESIGN AND SYNTHESIS OF BASE-METAL COORDINATION COMPLEXES AND THEIR APPLICATIONS AS CATALYSTS IN DIFFERENT ORGANIC TRANSFORMATIONS

Abstract

The thesis entitled “Design and Synthesis of Base-metal Coordination Complexes and their Applications as Catalysts in Different Organic Transformations” is reported in seven chapters. In the present work is aimed to design and synthesis of unsymmetrical salen-type ligands, pentadentate ligands, pincer-ligands and azo-based non-innocent ligands. These ligands were characterized through different analytical techniques such as UV-visible, IR, NMR, ESIMS and NMR spectroscopy. These ligands were utilized for the synthesis of manganese, iron, cobalt, nickel and copper complexes. These synthesized complexes were characterized by UVvisible, IR, NMR, ESI-MS spectroscopy. Complexes were characterized by X-ray crystallography. These complexes were utilized as catalysts for different organic transformation involving C−C, C−N bonds formation using different reactions like synthesis of tetrazoles and propargylamines, reduction of nitroaromatics, N‐alkylation and α‐alkylation of ketones with alcohols and synthesis of quinolines, quinazoline and quinazoli-4(3H)-ones. We have done the selective dimerization of ethylene to 1-butene using diethyl aluminium chloride (DEAC) as a co-catalyst. The synthesized compounds were characterized through different analytical techniques such as NMR analysis. We have also done some biological activity such as superoxide dismutase activity.