SYNTHESIS OF SOME HETEROCYCLIC COMPOUNDS AND THEIR CHARACTERIZATION

Abstract

A number of amidine derivatives were synthesized by condensation of 2-cyanopyridine, 4-cyanopyridine and 2-cyanopyrazine with amines in the presence of sodium methoxide. All the compounds, that is, III(a-f), IV(a-g), and V(a—d) were purified by crystallization or by column chromatography. Structures of all the synthesized and purified compounds are supported by correct IR, 'H NMR and mass spectral data reported in Table 1, 2, 3.